Estimation of phenolic conjugation by colonic mucosa.

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Estimation of phenolic conjugation by colonic mucosa.

Conjugation of phenol by the colonic mucosa was assessed in vivo using dialysis tubing containing 1.5 ml of 1 mmol/l acetaminophen (paracetamol) and 10 mmol/l butyrate. These were allowed to equilibrate in the rectum for one hour. The glucuronidated and sulphated conjugates of acetaminophen were measured by high pressure liquid chromatography and bicarbonate concentrations by gas analysis. In 2...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1989

ISSN: 0021-9746

DOI: 10.1136/jcp.42.6.620